Compared to other water-soluble vitamins, vitamin B12 isn’t excreted in urine, but is stored in the liver, kidney and other body cells. Hence, it may be five to six years before somebody actually develops a lack syndrome for vitamin B12. The general idea is that body shops do no exhaust before several years. The usual symptoms of vitamin B12 deficiencies are excessive , , listlessness, pallor and poor resistance to .


Elle peut également entraîner des changements neurologiques tels que des engourdissements et des picotements dans les pieds et les mains. D'autres symptômes peuvent inclure une sensibilité réduite à or pressure, blurred vision, abnormal gait, sore tongue, menstrual disorders and poor concentration levels. Instead of a dietary deficiency, a lack of vitamin B12 is usually related to a malabsorption of it. In such a scenario, the stomach can’t create enough of a substance called intrinsic factor (IF), which is a necessity for vitamin B12 absorption.

This type of condition, termed pernicious anemia, is an autoimmune disorder, wherein the body’s immune system attacks its own tissues. Vegetarians possibly at a risk for confronting deficiencies brought on by dietary reasons, because the only confirmed source for vitamin B12 intake is your animal resource. Vitamin B12 is necessary for the formation of red blood cells, and a brief supply of this causes anemia. A deficiency in Vitamin B12 also contributes to the disruption of DNA generation, and because of this, abnormal cells called megaloblasts happen, resulting in megaloblastic anemia.


La carence en vitamine B12 peut également être liée à différents troubles neurologiques et mentaux. Un manque de cobalamine profite au déclin cognitif, à la dégénérescence nerveuse et à des dommages neurologiques irréversibles, surtout chez les adultes de plus de cinquante ans. Les bébés nourris au sein de femmes qui suivent un régime végétarien strict ont des réserves très limitées de cette vitamine. Si elle n'est pas détectée, une carence en vitamine B12 chez les nourrissons peut entraîner des dommages neurologiques permanents.

Depression, dementia and Alzheimer’s disease can also be caused because of lack of vitamin B12. Other effects of deficiency may be asthma, , multiple sclerosis, tinnitus, diabetic neuropathy and reduced sperm counts. Ataxia (shaky movements and unsteady gait), , spasticity, incontinence, hypotension, eyesight problems, psychoses, and mood disturbances would be the other ailments that have recently been associated with potential vitamin B12 deficiencies.

Note finale

Women with breast cancer often have lower vitamin B12 levels in their blood serum. The causes of vitamin B12 deficiency might be liver damage brought on by excessive alcohol ingestion, gastrectomy (i.e. the surgical removal of part or all of the stomach or elimination of the ileum( a part of the gut ) and a bad performance of the . with Helicobacter pylori, a frequent cause of atrophic gastritis and peut également contribuer à une carence en vitamine B12 chez l'adulte.