People afflicted by week bones can recover with the support of stem cells, derived from pregnant women, according to a new study. The studies have shown us the stem cells harvested from the amniotic fluid of the pregnant women is the reply to osteoporosis, despite the fact that it was conducted on a mice model. The researchers had come to the decision after observing 78% lower hueso fractures among creatures, who had been suffering from brittle bone structures.
This finding has really evoked hope for those children, that are going through various rare bone ailments since birth in addition to adults, that suffer from osteoporosis. Not only that! This finding can also prove beneficial for the astronauts, who lost bone mass . Previous studies have proved that mesenchymal stem cells (MSCs) collected from an early stage are more powerful than that collected at a later stage. It has several other benefits also. Early taken MSCs have the capability to expand into larger numbers, when required in clinical treatments.
They do not form tumors. They make sure not to assault the sistema inmunológico of the receiver. They’re small thus can proceed easily. And last but not the least, these cells are easier to reprogram, so that they could grow into different kinds of cells. The researchers’ team at the University College London experimented with MSCs which were gathered from the amniotic fluid of pregnant women.
They injected the MSCs into mice with delicate bone ailments. Another interesting finding of this study was that the way the team finished the study. Anyone may think that the stem cells, injected into the mice, must have done the healing effects in addition to helped generating new bones primarily. But this is a wrong notion.
The study demonstrates that the stem cells released growth factors which stimulated the bone cells to build stronger bones in the mice model. Guillot confirmed,”The discovery could have a profound influence on the lives of individuals that have fragile bones and might stop a high number of their debilitating fracture.”
Following the successful study with mice, Guillot and the group are optimistic to use the procedure in treating brittle bone disorders and osteoporosis which affected over 44 million patients in america. The team is expecting to go about with the human trials over the next couple of decades. If the technique proves effective for individuals also, it may help children, affected in the womb and during birth. This procedure will truly help them build healthy bones. And what makes it even more intriguing is, the stem cells used in this research can be transplanted from one individual to another without MSCs matching between the donor and the recipient.